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Corel Medical Series: Cancer
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c36.dxr
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00032_Field_SRC.c36.C.5.txt
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1997-01-28
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421b
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• Many types of bone and soft tissue sarcoma have been found to have associated characteristic chromosome
abnormalities. Some families appear to have an increased incidence of sarcomas. Another inherited genetic
abnormality—deletion of the retinoblastoma gene—also increases risk.
• Some chemotherapeutic agents, particularly "alkylating" agents, increase risk of the development of cancer in
general.